Effects of transcranial alternating current stimulation on neurophysiologic motor function in Parkinson's patients: a systematic review and meta-analysis.

ABSTRACT:

Objective

This systematic review and meta-analysis aimed to evaluate whether tACS improves neurophysiologic motor function in patients with Parkinson's patients.

Methods

We searched PubMed, Embase, Web of Science, and Cochrane Library for eligible studies from inception to March 2025. Measured outcomes included two indicators of neurophysiologic function: motor evoked potentials and short-term intracortical inhibition. The Cochrane risk of bias tool was used to evaluate the quality of the included literature, and extracted data were qualitatively synthesized and meta-analyzed.

Results

Out of the 145 studies identified from the electronic databases, 7 fulfilled the inclusion criteria. Our results indicate that tACS significantly improved motor function in patients with

SUBMITTER: Ye F 

PROVIDER: S-EPMC12442322 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature