Trends and disparities in Non-Hodgkin Lymphoma related mortality in the United States, 1999-2020.

ABSTRACT:

Background

Non-Hodgkin Lymphoma (NHL) is the most prevalent hematological malignancy worldwide, making its mortality trends a critical public health concern. This study examines temporal trends in NHL-related mortality in the United States from 1999 to 2020, with a focus on sex-based, racial, and regional disparities.

Methods

Data were obtained from the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database. Crude and age-adjusted mortality rates (AAMR) were analyzed and annual percentage changes (APCs) were calculated using Joinpoint regression to identify temporal trends.

Results

Among 560,469 NHL-related deaths, AAMR declined from 12.86 (1999) to 8.26 per 100,000 (2020), with an increasing trend from 201

SUBMITTER: Saad M 

PROVIDER: S-EPMC12443298 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature