Benefits of INSTI-Based Regimens in a Real-World Setting of People Living With HIV-1 in Colombia.

ABSTRACT: Objective: The objective is to compare the clinical, virological, and immunological characteristics of people living with HIV-1 who were treated with first-line integrase inhibitors (INSTIs) versus those treated with other antiretrovirals. Methods: This is a descriptive observational, retrospective, two-center study. We selected individuals who began antiretroviral therapy (ART) within the first year of diagnosis and who had received at least 1 year of treatment. Their therapy consisted of two nucleoside/nucleotide reverse transcriptase inhibitors, along with a third medication (INSTI, nonnucleoside reverse transcriptase inhibitor (NNRTI), or protease inhibitor). The primary comparison was between individuals who initiated ART containing INSTIs and those who initiated ART con

SUBMITTER: Alzate-Angel JC 

PROVIDER: S-EPMC12443516 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature