Global lifetime estimates of expected and preventable gastric cancers across 185 countries.

ABSTRACT: Chronic infection with Helicobacter pylori is a modifiable cause of gastric cancer. To assist policymakers in advocating for and planning prevention strategies, we projected the future burden of gastric cancer, including that attributable to H. pylori, among a cohort of young people born in 2008-2017. Expected gastric cancer cases, in the absence of intervention, were quantified in 185 countries by combining national age-specific incidence rates from GLOBOCAN 2022 and cohort-specific mortality rates from the United Nations' demographic projections. Globally, 15.6 million (95% uncertainty interval 14.0-17.3 million) lifetime gastric cancer cases are expected within these birth cohorts, 76% of which are attributable to H. pylori. Two-thirds of cases will be concentrated in Asia, followed by

SUBMITTER: Park JY 

PROVIDER: S-EPMC12443596 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature