Open-source quality assurance for multi-parametric MRI: a diffusion analysis update for the magnetic resonance biomarker assessment software (MR-BIAS).

ABSTRACT:

Objective

To validate the automated analysis of magnetic resonance imaging (MRI) diffusion phantoms with an updated version of the magnetic resonance biomarker assessment software (MR-BIAS), an open-source tool initially developed for the analysis of MRI relaxometry phantoms.

Materials and methods

The updated MR-BIAS was validated against two published diffusion weighted MRI datasets: (i) a single-site study (n = 48) was used for validation of apparent diffusion coefficients (ADC) and to identify optimal region of interest (ROI) selection, and (ii) a multi-centre multi-vendor study including diffusion imaging from a shared benchmark protocol (n = 49) and site-specific protocols (n = 43). ADC analysis compared both datasets with ROIs manually matched to the original studies,

SUBMITTER: Korte JC 

PROVIDER: S-EPMC12443916 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature