A drug-based model to predict hyponatremia in outpatients of a geriatric clinic.

ABSTRACT:

Purpose

Chronic hyponatremia in older people is associated with adverse outcomes including gait disturbances, falls, osteoporosis, fractures, cognitive impairment, and cardiovascular disease. Diagnosis in outpatient settings is challenging due to the non-specific nature of its symptoms. While hyponatremia is well-studied in hospitalized patients, little research has focused on outpatient settings. This study aimed to develop a drug-based model to non-invasively predict hyponatremia in older adults attending a geriatric outpatient clinic.

Methods

Cross-sectional data from 2181 outpatients aged ≥ 55 were analysed using logistic regression. Polypharmacy, 27 specific drug groups, sex, age, and BMI were considered as potential risk factors. Predictors were selected using stepwise

SUBMITTER: van Orten-Luiten ACB 

PROVIDER: S-EPMC12443923 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature