A national cohort study of long-term opioid prescription and sociodemographic and health care-related risk factors.

ABSTRACT:

Background

Opioids are essential medicines for pain management; however, long-term use is associated with negative outcomes, including addiction. The aim of the study was to analyze the risk of long-term use after an initial opioid prescription and examine associated sociodemographic and health care-related risk factors.

Methods

We identified a strictly defined, five-year opioid-naïve population of adults aged 18-64 years who received an initial opioid prescription between 2016 and 2020 in Swedish national registers. We modeled the association between individual characteristics and odds of long-term ( > 3 months) versus short-term ( ≤ 3 months) use, and odds of different durations of use ( > 3-6, >6-12, and >12 months) using logistic regression analyses.

Results

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SUBMITTER: Kruger C 

PROVIDER: S-EPMC12443973 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature