Enhancing phenolic and flavonoid recovery from Vietnamese balm using green solvent-based ultrasonic-enzymatic-assisted extraction.

ABSTRACT: The research explored the extraction of phenolic and flavonoids from Elsholtzia ciliata (Vietnamese balm) using a natural deep eutectic solvent (NADES)-based ultrasonic-enzymatic-assisted extraction (UAE-EAE) technique. A range of NADESs was evaluated to investigate the most suitable solvent system. The NADES synthesized from lactic acid and choline chloride provided the highest recovery of phenolics and flavonoids. Single-factor experiments were conducted to assess how individual process variables influence the recovery of phenolics and flavonoids. Key factors affecting extraction performance were assessed using the Plackett-Burman approach. Optimal conditions were established through the Box-Behnken Design model. The optimal extraction parameters for TPhC were determined as a solid-to-li

SUBMITTER: Vo TP 

PROVIDER: S-EPMC12444158 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature