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Nutraceutical potential of moroccan <i>Juglans regia</i>: phytochemical profiling and multi-modal evaluation of bioactivities.


ABSTRACT: This study explores the therapeutic potential of J. regia from Morocco through an in-depth phytochemical analysis and biological evaluations using in vitro, in vivo, and in silico approaches. The extracts of J. regia were obtained through decoction and Soxhlet extraction, utilizing water and a water-ethanol mixture as extraction solvents. Phenolic compounds, flavonoids, condensed tannins, and hydrolyzable tannins were quantified using spectrophotometric methods. Chromatographic analysis by HPLC/MS enabled the identification and characterization of the main bioactive compounds. Biological activities were assessed through antioxidant (DPPH, FRAP, TAC), antimicrobial (MIC, MBC), anticoagulant (prothrombin time and activated partial thromboplastin time), and

SUBMITTER: Drioiche A 

PROVIDER: S-EPMC12444633 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature