Cu-Fe₃O₄ Nanoclusters-Loaded HAMA Hydrogel Patches for Multifunctional Synergistic Wound Healing.

ABSTRACT: Background: Skin wound healing is a common clinical challenge, facing multiple obstacles including delayed healing, local hypoxia, and bacterial infection, which may lead to prolonged nonhealing or wound infection. Traditional therapeutic strategies mostly intervene in single factors, making it difficult to achieve synergistic effects. Therefore, developing an innovative approach to simultaneously address multiple issues is of great significance. Objective: This study aims to develop a multifunctional hydrogel patch (Cu-Fe₃O₄-loaded HAMA, CFH) by integrating three core functions of promoting healing, supplying oxygen, and antibacterial activity, achieving a "one-for-three" therapeutic effect to provide a more comprehensive solution for wound repair. M

SUBMITTER: Zhou T 

PROVIDER: S-EPMC12444679 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature