Sequence-Controlled Neutral-Ionic Multiblock-Like Copolymers through Switchable PIESA in a One-Pot Approach.

ABSTRACT: Control over the composition and sequence of synthetic copolymers represents one of the most challenging targets in modern polymer science, in particular, for the labor- and time-consuming preparation of copolymers bearing ionic moieties. Though so far primarily focused on the assembly of coacervate nanostructures, we leverage polymerization-induced electrostatic self-assembly (PIESA) to achieve control over the composition and sequence of neutral-ionic copolymers and create complex chain topologies from equimolar mixtures of neutral and ionic monomers in a direct, one-pot process in aqueous solution. We are making use of the selective recruitment of charged over neutral monomers on an oppositely charged template to modulate monomer reactivities in situ during a controlled radical p

SUBMITTER: Sobotta FH 

PROVIDER: S-EPMC12444980 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature