Co-occurrence of Whole-body Muscle Wasting and Respiratory Muscle Weakness Affecting the Clinical Characteristics of Patients with Chronic Obstructive Pulmonary Disease.

ABSTRACT:

Objectives

The effect of the co-occurrence of whole-body muscle wasting and respiratory muscle weakness on the clinical characteristics of patients with chronic obstructive pulmonary disease (COPD) is unclear. We investigated this association in patients with chronic respiratory diseases.

Methods

47 outpatients with mild to very severe COPD were classified into four groups according to their fat-free mass index and respiratory muscle strength: 19 without muscle wasting and respiratory muscle weakness (normal), 6 with muscle wasting only (MW), 11 with respiratory weakness only (RW), and 11 with muscle wasting and respiratory weakness (MW + RW). We measured their body composition, pulmonary function, lower muscle strength, submaximal exercise capacity, physical activity in dai

SUBMITTER: Kawagoshi A 

PROVIDER: S-EPMC12445364 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature