Right atrial endomysial fibrosis is associated with increased postoperative atrial fibrillation burden during 2.5 years of continuous rhythm monitoring after cardiac surgery including atrial arrhythmia surgery: RACE V Tissue Bank Study.

ABSTRACT:

Aims

Several clinical factors, such as ageing and atrial dilatation, are associated with post-discharge atrial fibrillation (late-POAF) after cardiac surgery, but it is currently unknown if atrial histological characteristics are linked to late-POAF. Therefore, the aim of this study was to determine the association of atrial histological characteristics with POAF incidence and burden during 2.5 years of continuous rhythm monitoring after cardiac surgery.

Methods and results

Consecutive patients with and without AF history were prospectively included. Intraoperatively, biopsies were taken of left (LAA) and right atrial appendages (RAA), and all patients received an implantable loop recorder for 2.5 years. Biopsies were analysed for overall and endomysial fibrosis, cardiomyocy

SUBMITTER: Kawczynski MJ 

PROVIDER: S-EPMC12445663 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature