A Systematic Review of Algorithms for Identifying Pediatric Neurodevelopmental Outcomes.

ABSTRACT:

Purpose

Investigating pediatric neurodevelopmental outcomes (NDO) in studies using secondary data is often challenging due to heterogeneous clinical definitions and medical coding systems. This study aims to identify the algorithms used to define NDO in studies using electronic healthcare data through a systematic literature review.

Methods

A search strategy was developed to identify studies on NDO that describe phenotype algorithms from January 1, 2010, to March 10, 2025. The search strategy included terms to identify studies containing algorithms for NDO as an outcome, routinely collected healthcare data, epidemiologic designs likely to incorporate algorithms, and pregnant individuals and/or infants/children. Two independent reviewers assessed eligibility criteria and perf

SUBMITTER: Lopez-Leon S 

PROVIDER: S-EPMC12445936 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature