Age-stratified association between serum uric acid and lumbar bone mineral density in elderly Chinese women with vertebral compression fractures: a cross-sectional analysis.

ABSTRACT:

Objective

To investigate the association between serum uric acid (SUA) levels and lumbar bone mineral density (BMD) in elderly Chinese women with vertebral compression fractures (VCFs), with a specific focus on age-dependent variations in this association.

Methods

We conducted a cross-sectional study of 490 female patients aged ≥60 years with VCFs. SUA levels served as the primary exposure variable, and lumbar spine BMD was the outcome variable. Multivariate linear regression models were employed to adjust for potential confounders, incorporating comprehensive subgroup analyses.

Results

A statistically significant positive and independent correlation emerged between SUA levels and spine lumbar BMD after multivariable adjustment (β = 0.045, 95% CI 0.026-0.064).

SUBMITTER: Zhu J 

PROVIDER: S-EPMC12446221 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature