Effect of antioxidants on primary open-angle glaucoma: a systematic review and meta-analysis.

ABSTRACT:

Background/objectives

Primary open-angle glaucoma is a major global cause of vision loss, severely impacting quality of life. Although the need for effective treatments is widely recognized, the efficacy and safety of antioxidants remain uncertain. In this systematic review and meta-analysis, we aimed to evaluate the efficacy and safety of antioxidants in treating patients with primary open-angle glaucoma.

Methods

We reviewed studies from PubMed, Embase, Cochrane Library, and Web of Science published up to 30 November 2024. Eligible studies included adults aged 18-80 years with primary open-angle or normal-tension glaucoma, comparing antioxidant treatment with placebo or comparing a combination of topical treatment and antioxidants with topical treatment alone. Only randomiz

SUBMITTER: Bao J 

PROVIDER: S-EPMC12446234 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature