Visual acuity in various phenotypes of intermediate age related macular degeneration (AMD) in a multicentre cohort study in Europe- INTERCEPT-AMD report 1.

ABSTRACT:

Background/objectives

To study the associations of VA and intermediate age-related macular degeneration (iAMD) subclassifications.

Subjects/methods

This is the analysis of baseline data of a multicentre study on patients with iAMD in at least one eye. The subclassifications of iAMD were classified as: (i) iAMD with no evidence of incomplete retinal pigment epithelial and outer retinal atrophy (iRORA) or subretinal drusenoid deposits (SDD); (ii) iAMD with SDD with no iRORA; (iii) iAMD with iRORA with no SDD and (iv) iAMD with iRORA and SDD.

Results

983 eyes from 805 patients with iAMD were analysed. The mean age was 75.8 years (SD 7.9), with 35.0% (282) male. Eyes with iRORA with SDD had lower VA relative to eyes with no iRORA and no SDD (OR = 0.98 [95% CI 0.96, 0.998]

SUBMITTER: Gurudas S 

PROVIDER: S-EPMC12446473 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature