Thelaziosis in central Italy: Molecular detection of a variant haplotype in a human case and epidemiological aspects.

ABSTRACT: Thelazia callipaeda is an emerging zoonotic nematode responsible for ocular infection in Europe, transmitted by lachryphagous drosophilid flies of the genus Phortica. In this study, we updated the epidemiological picture of thelaziosis in Italy analysing parasites collected from a human case, in the vector Phortica variegata, and in a single naturally infected definitive host (dog), all from the same geographical area, the Latium region, central Italy. Median joining network and phylogenetic analyses based on the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene of T. callipaeda revealed a novel variant haplotype, named Haplotype 22, for the nematode from the human patient, distinct from the common Haplotype 1, detected for the nematodes fro

SUBMITTER: Cavallero S 

PROVIDER: S-EPMC12446669 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature