Association between hypertension and dementia risk in low- and middle-income countries: A systematic review.

ABSTRACT:

Background

Dementia prevalence is rising most rapidly in low- and middle-income countries (LMICs), yet most evidence on risk factors such as hypertension stems from high-income settings. In LMICs, hypertension may have a greater impact due to its high prevalence and poor control. We systematically reviewed evidence on the association between blood pressure and dementia and cognition in LMICs, and compared findings across regions.

Methods

We searched PubMed, Embase, PsycINFO, and Global Index Medicus and reviewed reference lists for relevant studies. We included longitudinal studies (follow-up ≥6 months) from LMICs on the association between systolic blood pressure or hypertension and incident dementia, mild cognitive impairment (MCI), or cognition, with a sample size of ≥500

SUBMITTER: Lindhout JE 

PROVIDER: S-EPMC12446671 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature