Ontology highlight
ABSTRACT: Background
Depression is common, burdensome, and is frequently first diagnosed in adolescents. The popular Adolescent Brain Cognitive Development dataset (ABCD) provides an attractive opportunity to research depression in adolescents. The only continuous measure of depression, as defined by DSM-5, in ABCD is the Child Behavior Checklist's DSM-5-Oriented Affective Problems scale (CBCL-Aff). We validated CBCL-Aff in the ABCD data and confirmed our results on two independent datasets: the Healthy Brain Network (HBN) and the Brazilian High Risk Cohort Study (BHRC).Methods
We tested Sensitivity, Specificity and Strict Specificity. Our participants were aged 8-11 years (ABCD) or 8-12 years (HBN, BHRC). Sample size was 183-1189 participants, depending on the analysis. Sample sizes
SUBMITTER: Zelenina M
PROVIDER: S-EPMC12446721 | biostudies-literature | 2025 Sep
REPOSITORIES: biostudies-literature