Surgical resection of a giant retroperitoneal dedifferentiated liposarcoma: a case report.

ABSTRACT:

Background

Liposarcoma (LPS) is a rare mesenchymal soft tissue sarcoma, and dedifferentiated liposarcoma (DDLPS) represents a clinically significant and aggressive subtype. Retroperitoneal DDLPS poses significant clinical challenges due to its insidious onset, large tumor size at the time of diagnosis, complex anatomical relationships, and high rates of recurrence and multi-organ involvement.

Case presentation

We present the case of a 64-year-old male who presented with a progressively enlarging abdominal mass, fatigue, and reduced appetite persisting for over five years. Imaging studies and interdisciplinary evaluation revealed a massive retroperitoneal tumor with invasion into multiple adjacent organs. The patient underwent comprehensive surgical resection involving the tu

SUBMITTER: Zhong S 

PROVIDER: S-EPMC12446831 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature