Prognostic Value of Handgrip Strength in Lung Cancer: Findings From a Multicenter Prospective Cohort Study.

ABSTRACT: BackgroundHandgrip strength (HGS), a simple and practical indicator of skeletal muscle function, has emerged as a potential prognostic marker, yet its predictive value in lung cancer remains to be fully elucidated. This study aimed to evaluate the prognostic significance of HGS for Overall Survival (OS) in patients with lung cancer, and to develop a prognostic model integrating HGS and hematologic parameters.MethodsThis prospective cohort study was based on the Investigation on Nutrition Status and its Clinical Outcome of Common Cancers (INSCOC). A total of 3604 pathologically confirmed lung cancer patients were included. Demographic, clinical, and nutrition-related data were collected. The association between HGS and OS was assessed using Cox proportional hazards models. A nomogram was de

SUBMITTER: Wang X 

PROVIDER: S-EPMC12446834 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature