Outcomes After Kidney Transplantation in Antiglomerular Basement Membrane Disease.

ABSTRACT:

Introduction

Goodpasture disease, or antiglomerular basement membrane (anti-GBM) disease, is a rare autoimmune disorder that often leads to end-stage kidney disease (ESKD). Although kidney transplantation (KT) is the preferred treatment, concerns exist about disease recurrence and graft outcomes in patients with GBM-associated glomerulonephritis (GBM-GN). This study aimed to evaluate posttransplant outcomes in patients with GBM-GN compared with matched controls.

Methods

This retrospective, multicenter study included 100 patients with anti-GBM who received KT between 2005 and 2023 in 13 French transplant centers, matched with 200 control recipients. We compared the incidence of delayed graft function (DGF), graft failure, relapse, acute rejection, and death between groups and

SUBMITTER: Traversat P 

PROVIDER: S-EPMC12446932 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature