Community-Acquired Acute Kidney Injury and Late Kidney Dysfunction in Survivors of COVID-19 Hospitalization.

ABSTRACT:

Introduction

Data on the incidence and risk factors for renal long COVID are scarce. We aimed to investigate 2 acute kidney injury (AKI) phenotypes, namely community-acquired (CA; CA-AKI) and hospital-acquired (HA; HA-AKI), and the development of late kidney dysfunction in survivors of COVID-19 hospitalization.

Methods

This is a prospective cohort study of survivors of moderate-to-severe COVID-19 hospitalization in Brazil, from March to August 2020. The patients were assessed for up to 11 months after hospital discharge. Exposure was CA-AKI and HA-AKI. The main outcome was kidney dysfunction defined as incident low estimated glomerular filtration rate (eGFR; < 60 ml/min per 1.73 m²) and/or eGFR decline ≥ 25% from discharge at follow-up. An adjusted binary logistic

SUBMITTER: Ribeiro HS 

PROVIDER: S-EPMC12446965 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature