A halogen bonding BODIPY-appended aza-crown ether for selective optical sensing of inorganic and organic ion-pair species.

ABSTRACT: A novel ion-pair receptor, consisting of a diaza-18-crown-6 cation binding motif and a BODIPY-appended halogen bonding optical anion-sensing motif, is prepared and shown to be a potent receptor for inorganic and organic ion-pairs. Comprehensive optical emission and ¹H NMR spectroscopic titration studies, in combination with computational investigations, demonstrate that the receptor exhibits significant selectivity for the ion-pair guest species K⁺/Cl^- over other alkali metal halide ion-pairs, and the neurotransmitter salt dopamine hydrochloride over other phenethylamine hydrochloride derivatives. Notably, the specific host-guest three-dimensional binding mode, resulting from the simultaneous participation of the heteroditopic receptor's multiple proximal c

SUBMITTER: Wilmore JT 

PROVIDER: S-EPMC12447292 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature