Ropivacaine Versus Bupivacaine in Pediatric Tonsillectomy: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

To evaluate the analgesic efficacy and safety of local anesthetic infiltration in the tonsillar fossa using ropivacaine compared to bupivacaine in pediatric patients undergoing tonsillectomy.

Data sources

CENTRAL, PubMed, Web of Science, Scopus, and Google Scholar.

Review methods

Eligible randomized controlled trials (RCTs) were evaluated for risk of bias using Cochrane's Risk of Bias Tool (RoB-2). The primary outcome was postoperative pain within the first 24 hours following tonsillectomy. Secondary outcomes included the time to first analgesic requirement and complication rates (ie, bleeding, airway obstruction, local anesthetic toxicity, and nausea). Data were synthesized using the standardized mean difference (SMD) for continuous outcomes and risk ratio

SUBMITTER: Albazee E 

PROVIDER: S-EPMC12447348 | biostudies-literature | 2025 Jul-Sep

REPOSITORIES: biostudies-literature