Xanthan Gum-Iron System: Natural, Mechanically Tunable, Bioactive, and Magnetic-Responsive Hydrogels for Biomedical Engineering Applications.

ABSTRACT: Xanthan gum (XG) has performed far better than other polysaccharides for industrial purposes, e.g., food, pharmaceutical, and cosmetic applications, due to its outstanding thickening effect, pseudoplastic rheological properties, and non-toxicity. However, there is no crosslinking strategy available for non-modified XG that allows its sole use within cells for biomedical engineering applications. Here, we established this crosslinking strategy while processing it via additive manufacturing techniques. The suitability of divalent (Ca²⁺, Mg²⁺, and Fe²⁺) and trivalent (Al³⁺ and Fe³⁺) ions was evaluated by an in situ rheological assessment. Fe³⁺ demonstrated a high affinity to XG by forming a stable crosslinking effect, and the b

SUBMITTER: Decarli MC 

PROVIDER: S-EPMC12447385 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature