Results of the Global Burden of Disease study for schizophrenia: trends from 1990 to 2021 and projections to 2050.

ABSTRACT:

Introduction

Schizophrenia represents a substantial aspect of the overall burden associated with mental disorders and ranks as the third leading cause of disability worldwide.

Methods

Utilizing data from the Global Burden of Disease (GBD), Injury, and Risk Factors Study, this research examines global trends in the prevalence, incidence, and disability-adjusted life years (DALY) attributable to schizophrenia, with stratification by age, sex, and socio-demographic index (SDI).

Results

Between 1990 and 2021, the prevalence of schizophrenia increased from 13.62 million to 23.18million, the incidence rose from 883,000 to 1.223 million, and the age-standardized disability rate (ASDR) escalated from 8.76 million to 14.82 million, reflecting increases of over 70.1%, 38.5%, an

SUBMITTER: Zhan Z 

PROVIDER: S-EPMC12447577 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature