Global burden of cirrhosis and other chronic liver diseases caused by specific etiologies from 1990 to 2021.

ABSTRACT:

Background

The global burden of cirrhosis and chronic liver diseases has remained substantial and continues to evolve in response to shifting etiological patterns. While viral hepatitis and alcohol use have historically dominated, non-alcoholic fatty liver disease (NAFLD) is emerging as a major contributor worldwide. A comprehensive understanding of these trends across regions and sociodemographic levels is essential for targeted public health interventions.

Methods

We analyzed data on cirrhosis and chronic liver diseases from 1990 to 2021 using estimates from the Global Burden of Disease (GBD) study. Age-standardized incidence rate (ASIR), prevalence rate (ASPR), mortality rate (ASMR), and disability-adjusted life years rate (ASDR) were assessed globally and across sociodem

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12447626 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature