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Prevention of RhD alloimmunization in the first trimester of pregnancy: Clinical practice guidelines of the French College of Obstetricians and Gynecologists.


ABSTRACT: The French College of Obstetricians and Gynecologists has decided to update its clinical practices guidelines for preventing RhD alloimmunization in the first trimester of pregnancy. The quality of evidence of the literature was assessed following the GRADE methodology with questions formulated in the Patients, Intervention, Comparison, Outcome (PICO) format and outcomes defined a priori and classified according to their importance. An extensive bibliographic search was performed using Pubmed, Cochrane, EMBASE, and Google Scholar databases. The quality of evidence was assessed (high, moderate, low, very low) and a recommendation was formulated: strong, weak, or no recommendation. The recommendations were reviewed in two rounds by members of the scientific board of the French College of Obs

SUBMITTER: Maurice P 

PROVIDER: S-EPMC12447672 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature