Clinical features and surgical options of obstructed hemivagina and ipsilateral renal agenesis (OHVIRA) syndrome: A systematic review and a meta-analysis of prevalence.

ABSTRACT:

Background

OHVIRA syndrome, a urogenital malformation, lacks standardized management. Narrative reviews exist, but there is no a comprehensive meta-analysis.

Objectives

The aim of this first systematic review and meta-analysis is to evaluate the current literature and inform management strategies.

Search strategy

We searched Scopus, Medline, Embase and Web of Science, up to March 2024.

Selection criteria

Case series, case reviews, and longitudinal studies on patients with OHVIRA syndrome.

Data collection and analysis

Data were extracted and meta-analyzed using R software.

Main results

In all, 35 studies (1988-2022) with 526 patients were included. Average symptom onset was 14.45 years, and diagnosis at 16.36 years suggests potential delays. The mo

SUBMITTER: Bonetti E 

PROVIDER: S-EPMC12447673 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature