Effects of perioperative intravenous esketamine on postoperative recovery quality in adult patients: a systematic review and meta-analysis.

ABSTRACT:

Objective

This study aimed to evaluate the effects of perioperative intravenous esketamine on the quality of postoperative recovery in adult patients.

Methods

The primary outcome was post-anesthesia care unit (PACU) stay time. Secondary outcomes included extubation time, Quality of Recovery-40 (QoR-40) and Quality of Recovery-15 (QoR-15) scores, pain scores at 24 hours postoperatively, incidence of postoperative nausea and vomiting (PONV), postoperative sleep quality, anxiety and depression, and mental side effects. A comprehensive literature search was conducted in PubMed, EMBASE, Web of Science, the Cochrane Library, and China National Knowledge Infrastructure from inception through April 20, 2023, with an update on May 18, 2024. The study was registered on PROSPERO (Regis

SUBMITTER: He Z 

PROVIDER: S-EPMC12447947 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature