Multistable bimodal perceptual coding within the ventral premotor cortex.

ABSTRACT: How neurons in the ventral premotor cortex (VPC) integrate and process multimodal sensory information remains unclear. We recorded VPC neuronal activity in two monkeys performing a tactile or acoustic bimodal detection task (BDT). Single-cell analyses revealed purely tactile, purely acoustic, bimodal, and decision-mnemonic responses. Population analyses of the VPC network and a recurrent neural network trained on the BDT uncovered notably similar latent dynamics. In both networks, neural trajectories diverged sharply from rest along modality-specific directions during stimulus presentation, while remained at rest during stimulus-absent trials. Subsequently, trajectories rotated toward a mnemonic subspace, where perceptual decisions (acoustic, tactile, and absent) were maintained in three d

SUBMITTER: Andrade-Ortega B 

PROVIDER: S-EPMC12448105 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature