Fibrosis 4 Index Predicts Haemocompatibility-Related Adverse Events in Patients Using Left Ventricular Assist Devices.

ABSTRACT:

Background

This study aimed to explore the association between the liver fibrosis-4 (FIB4) index and clinical events, specifically haemocompatibility-related adverse events (HRAEs), in patients who underwent left ventricular assist device (LVAD) implantation.

Methods

The study involved patients who received LVADs for advanced heart failure (HF) treatment. FIB4 index was calculated both preoperatively and postoperatively, and its association with clinical events was examined, focusing on all-cause mortality and HRAEs, which included severe bleeding, cerebrovascular accidents, and intra-pump thrombosis.

Results

A total of 224 patients with LVAD were analyzed. The value of FIB4 index was significantly decreased after LVAD implantation, and the postoperative FIB4 index wa

SUBMITTER: Kurihara T 

PROVIDER: S-EPMC12448308 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature