Association Between Blood Culture Bottle Shortage and Ordering Restrictions and Clinical Outcomes for Patients With <i>Staphylococcus aureus</i> Bacteremia.

ABSTRACT:

Background

A nationwide shortage of blood culture bottles led to significant restriction of blood culture utilization at our institution.

Methods

We evaluated the impact of 3 combined interventions: (1) guidance on appropriate blood culture utilization, (2) restriction of repeat cultures within a 48-hour period, and (3) restriction of initial assessment to a single blood culture set consisting of 1 aerobic and 1 anaerobic blood culture bottle, on the management of patients with Staphylococcus aureus bacteremia (SAB) using an interrupted time series analysis.

Results

Prior to the intervention, 90.1% of patients had 2 blood culture sets ordered for initial assessment, versus 5.7% during the intervention and 84.1% postintervention. The median number of cultures to

SUBMITTER: Humphries RM 

PROVIDER: S-EPMC12448447 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature