Genetic suppressors of the growth-immunity trade-off in the Arabidopsis salicylic acid-accumulating dmr6 dlo1 mutant.

ABSTRACT: Plants actively suppress growth and development upon activation of immunity. In turn, when pathogen attack has subsided, immune responses are suppressed again. Phytohormones play an important role in regulating this balance and the growth-immunity trade-off in general. The trade-off is evident in the Arabidopsis dmr6 dlo1 mutant, which accumulates the immune-activating phytohormone salicylic acid (SA) to high levels, resulting in high disease resistance but repression of growth. Little is known about the SA-induced growth trade-off mechanism. In this study, we performed a genetic suppressor screen on the dmr6 dlo1 double mutant to select mutants with reduced growth repression and identify suppressors of the SA-mediated trade-off. We identified 7 independent zund (giant) mutants, with resto

SUBMITTER: van Butselaar T 

PROVIDER: S-EPMC12448671 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature