Association of glutamine supplementation during the early suckling period with growth, weaning, and lipopolysaccharide induced stress in low birthweight piglets.

ABSTRACT: Glutamine (Gln) supplementation has been shown to improve bodyweight (BW) in suckling low birthweight (LBiW) pigs. However, it is not known if Gln has lasting effects on growth and stress resilience beyond the supplementation period in LBiW suckling pigs. Therefore, we explored if post-Gln supplementation LBiW pigs show reduced stress during weaning and a lipopolysaccharide challenge. Twenty pairs of male German Landrace littermate piglets, originating from 14 L with 12 to 22 (live and stillborn) piglets, were selected at birth (0 d of age). One littermate was LBiW (mean 1.10 ± 0.02 kg; n = 20; below the lowest BiW quartile of the FBN pig facility) and the other normal (NBiW; mean 1.48 ± 0.02 kg; n = 20; within the middle 50th BiW quartile) birthweight. At 24 h postfarrowing, litter sizes

SUBMITTER: Sciascia QL 

PROVIDER: S-EPMC12448690 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature