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ABSTRACT: Introduction
Rapidly acting and highly effective management approaches are critically needed for potentially life-threatening and career-ending stings by box jellyfish (phylum Cnidaria, class Cubozoa) among underwater-operation warfighters working in austere environments. Cubozoan envenomation results in venom load- and time-dependent complex sequelae, including acute-phase hemolysis, cardiorespiratory collapse, hypovolemic shock, and death. Despite previously published studies demonstrating the failure of various generally advised, lay first-aid approaches (including fresh-water rinsing, ice-pack application, and skin scraping) to inhibit box jellyfish venom-induced hemolysis and tissue damage in vitro, ineffective and even deleterious management practices persist. In this report,
SUBMITTER: Yanagihara AA
PROVIDER: S-EPMC12448702 | biostudies-literature | 2025 Sep
REPOSITORIES: biostudies-literature