Perinatal colonization with extended-spectrum beta-lactamase-producing and carbapenem-resistant gram-negative bacteria among home births in Bangladesh.

ABSTRACT:

Background

Neonatal infections are increasingly caused by antibiotic-resistant bacteria. It is unknown to what extent home-based births, which account for nearly a third of deliveries in Bangladesh, may also result in exposure to antibiotic-resistant bacteria.

Methods

We enrolled mothers who delivered at home and their newborns from a rural community in Bangladesh during April-June, 2022. Within 2-7 days after delivery, we collected vaginal and rectal swabs from mothers and rectal swabs from the newborns. Swabs were cultured on chromogenic culture media selective for extended-spectrum β-lactamase-producing bacteria (ESBL-PB) and carbapenem-resistant bacteria (CRB). Demographic and risk factor data were collected via surveys. Birth attendants who facilitated the deliveries we

SUBMITTER: Wu GS 

PROVIDER: S-EPMC12448980 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature