Using injectable Platelet-Rich fibrin to improve recovery after impacted lower third molar extraction: a randomized controlled clinical trial.

ABSTRACT:

Objectives

The aim of this RCT was to clinically evaluate swelling, pain and wound healing following submucosal infiltration of injectable Platelet-Rich Fibrin (i-PRF) after extraction of impacted lower third molar.

Materials and methods

The study was designed as a double-blinded, parallel group, randomized controlled clinical trial. 56 patients were divided into 2 groups: in the control group the socket was left to heal spontaneously, while the test group was treated with submucosal infiltration of i-PRF. Swelling was measured with a flexible ruler using the diagonals joining Trago and Pogonion, Gonion and labial cleft. The swelling was calculated as the sum of these diagonals before surgery, on day 3 and 7. Pain was assessed by VAS scale until the 7th postoperative day. Su

SUBMITTER: Aliberti A 

PROVIDER: S-EPMC12449355 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature