Moderate Kidney Dysfunction Independently Increases Sudden Cardiac Arrest Risk: A Community-Based Study.

ABSTRACT:

Background

Moderate kidney dysfunction is independently associated with increased cardiovascular death. Sudden cardiac arrest (SCA) accounts for at least 25% of chronic kidney disease (CKD) death. This study aimed to evaluate the impact of moderate CKD on SCA risk.

Methods

We conducted a case-control study within a community-based investigation of SCA in the Portland, Oregon, metropolitan area from February 1, 2002, to December 31, 2020. Analysis included individuals aged 40 to 75 years who experienced SCA (cases) and individuals with no history of SCA (controls), with creatinine levels measured before SCA/enrollment. Moderate CKD was defined by an estimated glomerular filtration rate of 30 to <60 mL/min per 1.73 m² (2021 Chronic Kidney Disease Epidemiology Collab

SUBMITTER: Truyen TTTT 

PROVIDER: S-EPMC12449910 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature