Comparative Evaluation of Resting and Hyperemic Angiography-Derived Index of Microcirculatory Resistance in Chronic Coronary Syndrome.

ABSTRACT:

Background

Angiography-derived index of microcirculatory resistance (IMR) has emerged as a feasible alternative to wire-based IMR, due to the elimination of specialized wire and simplifying of the procedure. However, the differences in diagnostic accuracy between hyperemic and resting angiography with this technology remain underexplored.

Methods

This prospective, multicenter study was conducted to evaluate the feasibility and diagnostic accuracy of x-ray angiography-derived IMR (xaIMR) in patients with chronic coronary syndrome using wire-based functional indices as the reference. Angiography-derived functional indices were calculated using a computational fluid dynamics model. The xaIMR indices were derived from hyperemic and resting angiography, respectively.

Results</

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12449942 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature