Coronary Atherosclerosis and Subclinical Cerebral Small Vessel Disease: A Robust Association Beyond Intracranial Atherosclerosis and Cardiac Systolic Function.

ABSTRACT:

Background

This study investigates the associations between asymptomatic coronary atherosclerosis and subclinical cerebral small vessel disease (CSVD) in a community-based population, considering potential confounding by intracranial atherosclerosis and cardiac systolic function.

Methods

Community-dwelling residents from the PRECISE (Polyvascular Evaluation for Cognitive Impairment and Vascular Events) study in Lishui City, China (n=3021; mean age, 61.2±6.4 years; 46.4% male), underwent assessment of coronary and intracranial atherosclerotic burden via coronary computed tomography angiography and high-resolution magnetic resonance imaging. CSVD burden and imaging markers (white matter hyperintensities, lacunes, enlarged perivascular spaces, and cerebral microbleeds) were eva

SUBMITTER: Wang Z 

PROVIDER: S-EPMC12449956 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature