Clinical Impact of Early Changes in Serum Albumin on Patient Prognosis After Mitral-Transcatheter Edge-to-Edge Repair.

ABSTRACT:

Background

Low serum albumin levels indicate frailty and are strong predictors of poor prognosis after mitral transcatheter edge-to-edge repair (M-TEER); however, albumin levels are expected to improve in response to treatment for mitral regurgitation. No reports have elucidated the clinical effects of albumin changes after M-TEER. Thus, we aimed to explore the association between early albumin changes and clinical outcomes after M-TEER and to identify the associated factors.

Methods

Data from 2695 patients enrolled in a Japanese multicenter registry whose serum albumin levels were measured before and 1 month after undergoing M-TEER were retrospectively reviewed. Changes in albumin (Δ-albumin) were calculated and divided into 2 groups, namely improved albumin (Δ-albumin >0)

SUBMITTER: Shibata K 

PROVIDER: S-EPMC12449999 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature