Association Between Size of Left Ventricle and Long-Term Cardiovascular Events.

ABSTRACT:

Background

The prognostic significance of small left ventricle (LV) in the general population and its association with cardiovascular disease remain elusive.

Methods

Using data from the UK Biobank, 39 363 participants underwent baseline cardiovascular magnetic resonance imaging and were categorized into 3 groups based on left ventricular end-diastolic volume index: small, normal, and large LV. Cox proportional hazards models were applied to evaluate the association between LV size and composite cardiovascular outcomes.

Results

An elevated prevalence of small LV was observed among the 4305 participants, with a notable trend toward increased occurrence in older individuals. Over a median follow-up of 5.21 years, 1500 cases of major adverse cardiovascular events, 1096 co

SUBMITTER: Cheng YJ 

PROVIDER: S-EPMC12450011 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature