Construct validity of automated assessment of invasively measured hemodynamics during transcatheter aortic valve replacement.

ABSTRACT:

Aims

Paravalvular regurgitation (PVR) is frequently observed following Transcatheter Aortic Valve Replacement (TAVR). Periprocedural monitoring of invasive hemodynamics has shown promise for diagnosis of PVR, but automated software options are lacking. We aimed to develop a rule-based algorithm for automated assessment of hemodynamic indices of PVR, and evaluate its construct validity and discriminatory value for cardiac magnetic resonance (CMR)-derived relevant PVR compared to standard manual hemodynamic assessment.

Methods and results

Left ventricular and aortic pressures were invasively measured during TAVR using fluid-filled pigtail catheters. To evaluate construct validity of automated vs. manual assessment of invasive hemodynamics, we compared (i) proportion of cardiac

SUBMITTER: Stens NA 

PROVIDER: S-EPMC12450506 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature