Antiseptic susceptibility profiles of canine pyoderma-associated staphylococci in Japan: first identification of plasmid-borne <i>smr</i> in <i>Staphylococcus coagulans</i>.

ABSTRACT:

Introduction

International guidelines recommend the use of antiseptics, such as chlorhexidine, to treat canine pyoderma. However, data on the antiseptic susceptibility of its primary causative agents, Staphylococcus pseudintermedius and S. coagulans, in Japan are limited.

Methods

We performed antiseptic susceptibility testing and polymerase chain reaction (PCR) screening for antiseptic resistance-associated genes in these species. In addition, hybrid genome sequencing was conducted for a resistant isolate to investigate the genetic context of resistance genes.

Results

Most isolates exhibited low minimum inhibitory concentrations for the tested antiseptics, although some inter-strain variations were observed. One S. coagulans isolate (SC18) was ide

SUBMITTER: Tsunoi M 

PROVIDER: S-EPMC12450657 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature