Visuospatial processing in patients with Alzheimer's disease and cerebral amyloid angiopathy.

ABSTRACT:

Introduction

There is a well-established but poorly understood pathological and clinical overlap between cerebral amyloid angiopathy (CAA) and Alzheimer's disease (AD). Some studies have suggested a posterior predominance of CAA-related lesions, but it remains unclear how well this can be captured by specific measures of low- to high-level visual cortical processing.

Methods

We compared the characteristics of 30 patients with AD and/or CAA, grouped by impairment measures of low- to mid-level visual cortical processing, and explored associations with clinical characteristics, neurodegeneration biomarkers, CAA imaging features, and volumetric structural measures.

Results

Twenty participants were classified as impaired on tasks of low- to mid-level visual cortical functi

SUBMITTER: Costa AS 

PROVIDER: S-EPMC12450703 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature