The pulmonary artery pulsatility index in patients with severe aortic stenosis undergoing valve replacement.

ABSTRACT:

Background and aims

The pulmonary artery pulsatility index (PAPi), that is, the pulmonary artery pulse pressure (PAPP) divided by the mean right atrial pressure (mRAP), is an increasingly used invasive index of right ventricular function. We sought to assess the prognostic impact of the PAPi in unselected patients with aortic stenosis (AS) undergoing aortic valve replacement (AVR).

Methods

We studied consecutive patients with severe AS (n = 487, 74 ± 10 years, 58% males) undergoing right heart catheterization prior to AVR with post-AVR follow-up of several years.

Results

The mean PAPi was 4.7 ± 3.3, and the mean values in the four PAPi quartiles were 2.1 ± 0.5, 3.2 ± 0.3, 4.5 ± 0.5 and 8.9 ± 4.2. Patients in the lowest PAPi quartile had similar AS severity, symptoms,

SUBMITTER: Rechsteiner LA 

PROVIDER: S-EPMC12450790 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature