Atrial fibrillation and flutter as global drivers of heart failure: Burden and longitudinal trends over three decades.

ABSTRACT:

Aims

The study aims to comprehensively evaluate the global burden of heart failure attributable to atrial fibrillation (AF) and atrial flutter (AFL) from 1990 to 2021.

Methods

Using data from the Global Burden of Disease Study 2021, we estimated the prevalence and years lived with disability (YLDs) of heart failure attributable to AF/AFL across 204 countries and territories. Estimates were stratified by age, sex and socio-demographic index (SDI). Age-standardized rates per 100 000 population were calculated, and percentage changes between 1990 and 2021 were analysed to assess temporal trends.

Results

In 2021, AF/AFL were responsible for an estimated 714 137.5 [95% uncertainty interval (UI) 520 543.5 to 940 900.6] heart failure cases and 63 942.8 (95% UI 39 057.9 to 96

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12450823 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature